Eastern Bhutan is the least traveled area of the country and is where many of the kingdom's most ancient spiritual sights are found.

This region comprises Mongar, Lhuentse, Trashigang and Trashi Yangste. Sengor Valley separates Central from Eastern Bhutan. After Thrumshing La, passes crossed are Kori La (2400m), Yongphu La (2190m) and Narphung La (1698) at much lower altitudes than Western and Central. The forests dissipate and the altitude is lower. The warmer climate is suitable for growing corn, rice, wheat, potatoes and surprisingly lemon grass. Eastern Bhutan is known for its stunning hand-loomed textiles and the weavers are all masters of the supplementary weft-weave technique.

Many towns in eastern Bhutan are built on the sides of the hills which contrasts to the west where they develop on the valley floor.